abstract：:It is not known whether dexamethasone increases the effectiveness of anti-emetics when given to treat postoperative nausea and vomiting (PONV). In a randomised study, 242 patients who were experiencing PONV received dolasetron and placebo, haloperidol and placebo, dolasetron and dexamethasone, or haloperidol and dexam...

journal_title：Anaesthesia

authors： Rüsch D,Arndt C,Martin H,Kranke P

更新日期：2007-08-01 00:00:00

abstract：:Target controlled infusion (TCI) pumps function using a programme based on a pharmacokinetic/pharmacodynamic model. We compared the Marsh and Schnider models to find out which better correlates with the clinically observed effect of propofol as assessed by the Observer Assessment of Alertness/Sedation (OAAS) score and...

journal_title：Anaesthesia

authors： Barakat AR,Sutcliffe N,Schwab M

更新日期：2007-07-01 00:00:00

abstract：:The Laryngeal Tube S and the LMA-ProSeal are supraglottic instruments with an improved airway seal and a drainage tube to protect against regurgitation and to facilitate passage of a gastric tube. We compared the feasibility of these two instruments in a randomised, controlled clinical trial. One hundred and sixty pat...

journal_title：Anaesthesia

authors： Klaver NS,Kuizenga K,Ballast A,Fidler V

更新日期：2007-07-01 00:00:00

abstract：:Haemodynamic instability is a recognised phenomenon in critically ill patients undergoing hyperbaric therapy. Instability may result from the effects of ambient pressure on the cardiovascular system, devices involved in infusion of drugs and fluids, or a combination of the two. The effect of hyperbaric pressure on air...

journal_title：Anaesthesia

authors： Hopson AS,Greenstein A

更新日期：2007-06-01 00:00:00

abstract：:Transoesophageal echocardiography (TOE) requires extensive hands-on training, and it is for this purpose we have designed EchoComTEE, a simulator for TOE. It consists of a manikin and dummy probe; according to the position of the dummy probe (tracked by an electromagnetic sensor), two-dimensional (2D) images are calcu...

journal_title：Anaesthesia

authors： Weidenbach M,Drachsler H,Wild F,Kreutter S,Razek V,Grunst G,Ender J,Berlage T,Janousek J

更新日期：2007-04-01 00:00:00

abstract：:We describe a patient with type 2N von Willebrand's disease scheduled for elective coronary artery bypass graft for severe three-vessel coronary artery disease with involvement of the left main stem. He was given a pre-operative bolus of 3000 IU factor VIII/Willebrand factor concentrate (approximately 40 IU.kg(-1)), f...

journal_title：Anaesthesia

authors： Gerling V,Lahpor JR,Buhre W

更新日期：2007-04-01 00:00:00

abstract：:Recovery from a critical illness can be delayed by persistent anxiety and depression. To identify such patients, a new self-report questionnaire (the Depression, Anxiety and Stress scale, DASS) was used alongside an established instrument (the Hospital Anxiety and Depression scale, HADS) in those who had spent a minim...

journal_title：Anaesthesia

authors： Sukantarat KT,Williamson RC,Brett SJ

更新日期：2007-03-01 00:00:00

abstract：:Transoesophageal echocardiography measures of systolic left ventricular function obtained during coronary artery bypass surgery are heavily influenced by alterations in loading conditions. No validation of these measurements against load independent indices obtained by pressure-volume loop analysis has been undertaken...

journal_title：Anaesthesia

authors： Royse CF,Connelly KA,MacLaren G,Royse AG

更新日期：2007-02-01 00:00:00

abstract：:We present 14 cases, of which three have been previously reported, in which non-conventional use was made of the Aintree Intubating Catheter (AIC). In seven cases the AIC was used via a ProSeal Laryngeal mask airway (PLMA). Two patients had anticipated difficult intubation, two unexpected difficult intubation and two ...

journal_title：Anaesthesia

authors： Cook TM,Seller C,Gupta K,Thornton M,O'Sullivan E

更新日期：2007-02-01 00:00:00

abstract：:A neurosurgical patient who required repeated surgery for intracranial haematoma developed acute respiratory distress syndrome. Raised intracranial pressure proved difficult to manage whilst attempting to maintain optimal gas exchange. The resultant arterial partial pressure of carbon dioxide remained unacceptably hig...

journal_title：Anaesthesia

authors： Mallick A,Elliot S,McKinlay J,Bodenham A

更新日期：2007-01-01 00:00:00

abstract：:We describe the use of a questionnaire to define the difficulties in providing anaesthesia in Uganda. The results show that 23% of anaesthetists have the facilities to deliver safe anaesthesia to an adult, 13% to deliver safe anaesthesia to a child and 6% to deliver safe anaesthesia for a Caesarean section. The questi...

journal_title：Anaesthesia

authors： Hodges SC,Mijumbi C,Okello M,McCormick BA,Walker IA,Wilson IH

更新日期：2007-01-01 00:00:00

abstract：:As the incidence of diabetes mellitus continues to increase in the United Kingdom, more diabetic patients will present for both elective and emergency surgery. Whilst the underlying pathophysiology of type 1 and type 2 diabetes differs, there is much good evidence that controlling the blood glucose to < or = [correcte...

journal_title：Anaesthesia

authors： Robertshaw HJ,Hall GM

更新日期：2006-12-01 00:00:00

abstract：:There is an ongoing debate as to whether propofol exhibits pro- or anticonvulsant effects, and whether it should be used in patients with epilepsy. We prospectively assessed the occurrence of seizure-like phenomena and the effects of intravenous propofol on the electroencephalogram (EEG) in 25 children with epilepsy (...

journal_title：Anaesthesia

authors： Meyer S,Shamdeen MG,Kegel B,Mencke T,Gottschling S,Gortner L,Grundmann U

更新日期：2006-11-01 00:00:00

abstract：:We conducted a randomised controlled trial to compare the efficacy of forced-air warming (Bair Hugger(trade mark), Augustine Medical model 500/OR, Prairie, MN) with that of an electric heating pad (Operatherm 202, KanMed, Sweden) for maintenance of intra-operative body temperature in 60 patients undergoing total knee ...

journal_title：Anaesthesia

authors： Ng V,Lai A,Ho V

更新日期：2006-11-01 00:00:00

abstract：:We performed a retrospective audit of blood glucose control after introducing a new protocol for insulin infusion. The audit showed a sustained reduction in the median blood glucose, which decreased from 7.0 to 6.8 mmol x l(-1), primarily because of a reduction in the proportion of values above 6 mmol x l(-1). When we...

journal_title：Anaesthesia

authors： Bone EG,Young D,Chantler J

更新日期：2006-10-01 00:00:00

abstract：:We conducted a randomised study in 70 patients to assess the effect of orientation of a standard polyvinyl chloride tracheal tube on the ease of railroading the tube during awake fiberoptic orotracheal intubation. Conventional orientation of the tube (with the bevel of the tube directed to the patient's left) was comp...

journal_title：Anaesthesia

authors： Sharma D,Bithal PK,Rath GP,Pandia MP

更新日期：2006-09-01 00:00:00

abstract：:Over-running operating lists are known to be a common cause of cancellation of operations on the day of surgery. We investigated whether lists were overbooked because surgeons were optimistic in their estimates of the time that operations would take to complete. We used a questionnaire to assess the estimates of total...

journal_title：Anaesthesia

authors： Pandit JJ,Carey A

更新日期：2006-08-01 00:00:00

abstract：:Traditional medical decision making is unstructured and incorporates evidence haphazardly. I present a more structured approach based on decision analysis, a model that considers all relevant options and outcomes informed by evidence where appropriate. This method is useful both for planning clinical management and fo...

journal_title：Anaesthesia

authors： Yentis SM

更新日期：2006-07-01 00:00:00

abstract：:Nerve stimulation is considered by many to be the current 'gold standard' for locating peripheral nerves. Thirteen nerve stimulators were subjected to a battery of tests performed by two independent observers under standardised conditions using a digital oscilloscope, a calibrated resistance and a novel scoring system...

journal_title：Anaesthesia

authors： Jochum D,Iohom G,Diarra DP,Loughnane F,Dupré LJ,Bouaziz H

更新日期：2006-06-01 00:00:00

abstract：:We report two patients with difficult airways who underwent tracheal intubation using the new fibreoptic intubating Laryngeal Mask Airway CTrach. The imaging technology of the LMA-CTrach was decisive in the management of these two patients. The first patient had lingual tonsillar hyperplasia, and an omega-shaped retro...

journal_title：Anaesthesia

authors： Goldman AJ,Rosenblatt WH

更新日期：2006-06-01 00:00:00

abstract：:The extent of a regional block for Caesarean section must be tested and documented before surgery commences. In recent years a block to 'touch' that includes T5 has increasingly been considered the best predictive test for a pain-free Caesarean section. Our survey examines the consistency with which different anaesthe...

journal_title：Anaesthesia

authors： Congreve K,Gardner I,Laxton C,Scrutton M

更新日期：2006-05-01 00:00:00

abstract：:Supraglottic airway devices such as the ProSeal Laryngeal Mask Airway (PLMA) and Laryngeal Tube-Suction Airway (LTS) that provoke the least stress responses could be beneficial in many situations, especially in patients with cardiovascular disease. We compared the haemodynamic and catecholamine stress response of the ...

journal_title：Anaesthesia

authors： Dahaba AA,Prax N,Gaube W,Gries M,Rehak PH,Metzler H

更新日期：2006-04-01 00:00:00

abstract：:The Mental Capacity Act 2005 is due to come into force in April 2007. The Act provides a protective statutory framework for decision-making on behalf of incompetent adults, representing, in the main, a codification of the common law that had already developed in this area. For example, 'advance decisions' are now give...

journal_title：Anaesthesia

authors： White SM,Baldwin TJ

更新日期：2006-04-01 00:00:00

abstract：:Subclinical renal dysfunction is thought to occur as a systemic manifestation of ischaemia-reperfusion injury of other organs. Liver transplantation is associated with major ischaemia-reperfusion injury. Thirty-four patients undergoing elective liver transplantation were randomly allocated to receive either saline or ...

journal_title：Anaesthesia

authors： Turner S,Dhamarajah S,Bosomworth M,Bellamy MC,Leeds Liver Transplant Group.

更新日期：2006-03-01 00:00:00

abstract：:Many new supraglottic airway devices have been recently introduced, their development motivated by the need for a single-use equivalent to the original re-usable laryngeal mask airway. We performed a randomised cross-over study in spontaneously breathing patients comparing the re-usable Laryngeal Mask Airway-Classic (...

journal_title：Anaesthesia

authors： Shafik MT,Bahlman BU,Hall JE,Ali MS

更新日期：2006-02-01 00:00:00

abstract：:We assessed the use of intravenous remifentanil for the insertion of the laryngeal mask airway in 10 healthy awake volunteers, a technique primarily developed to facilitate functional magnetic resonance imaging studies of anaesthesia. Each volunteer received 200 microg glycopyrronium intravenously. Topical airway anae...

journal_title：Anaesthesia

authors： Lee MC,Absalom AR,Menon DK,Smith HL

更新日期：2006-01-01 00:00:00

abstract：:We have compared the performance of the single use laryngeal airway devices Softseal and LMA-Unique in a randomised comparative trial in anaesthetised healthy patients who did not receive neuromuscular blockade. Primary outcome was success of airway placement. Secondary outcomes included manipulations and complication...

journal_title：Anaesthesia

authors： Cook TM,Trümpelmann P,Beringer R,Stedeford J

更新日期：2005-12-01 00:00:00

abstract：:Amniotic fluid embolism is a rare obstetric complication. The exact pathogenesis of this syndrome remains unknown and significant controversy exists whether coagulopathy should always be present. We used thromboelastography to assess the effect of amniotic fluid on coagulation and platelet function in pregnant women. ...

journal_title：Anaesthesia

authors： Harnett MJ,Hepner DL,Datta S,Kodali BS

更新日期：2005-11-01 00:00:00

abstract：:The Fontan procedure is performed for patients with a hypoplastic right ventricle, and pregnancies following this palliative surgery are likely to increase. We present a parturient with the Fontan physiology who successfully underwent two consecutive caesarean deliveries; the first under general anaesthesia for emerge...

journal_title：Anaesthesia

authors： Eid L,Ginosar Y,Elchalal U,Pollak A,Weiniger CF

更新日期：2005-11-01 00:00:00

abstract：:Summary The aim of this study was to compare the accuracy of pulse dye densitometry with that of bolus thermodilution cardiac output measurement in patients before and after elective coronary artery bypass grafting. Twenty-eight patients were studied. Agreement between mean thermodilution and pulse dye densitometry ca...

journal_title：Anaesthesia

authors： Baulig W,Bernhard EO,Bettex D,Schmidlin D,Schmid ER

更新日期：2005-10-01 00:00:00

abstract：:Enteral tube feeding is widely used in intensive care units, high dependency units and general wards. In some patients, an adequate intake is not maintained because patients cannot tolerate the tube. Insertion of an enteral feeding tube via a pharyngostomy is simple and potentially more easily tolerated. We describe o...

journal_title：Anaesthesia

authors： Jones TM,Bodenham AR

更新日期：2005-10-01 00:00:00

abstract：:We have proposed an equation for estimating the real-time mixed venous blood concentration (MVBC) of isoflurane in cardiac anaesthesia. However, information related to the application of our method to sevoflurane is lacking. We studied 12 patients undergoing cardiac surgery and anaesthetised with sevoflurane. At diffe...

journal_title：Anaesthesia

authors： Ho WM,Hung WT,Wu CC,Shen CH,Yang NC,Hwang KL,Wong KC

更新日期：2005-09-01 00:00:00

abstract：:Primary tracheostomy under local anaesthesia is indicated in the management of an anticipated difficult airway in patients in whom less invasive procedures are expected to fail or have already failed. However, primary tracheostomy is a relatively complex procedure and places not inconsiderable stress on the patient. I...

journal_title：Anaesthesia

authors： Gerig HJ,Schnider T,Heidegger T

更新日期：2005-08-01 00:00:00

abstract：:This review summarises the physiological and pharmacological effects of the anabolic steroids used to enhance performance in sports. The anabolic steroids promote muscle growth and protein synthesis. Side-effects of anabolic steroids include cardiomyopathy, atherosclerosis, hypercoagulopathy, hepatic dysfunction, and ...

journal_title：Anaesthesia

authors： Kam PC,Yarrow M

更新日期：2005-07-01 00:00:00

abstract：:Functional capacity is an integral component of the pre-operative evaluation of the cardiac patient for non-cardiac surgery. Stair climbing capacity has peri-operative prognostic importance. It may predict survival after lung resection and complications after major non-cardiac surgery. However, stair climbing cannot d...

journal_title：Anaesthesia

authors： Biccard BM

更新日期：2005-06-01 00:00:00

abstract：:Opioid induced respiratory depression is potentially fatal. The aim of this study was to validate a monitoring system that could be used to assess respiratory depression in postoperative patients. The hypercapnic ventilatory response was estimated non-invasively in 12 volunteers. In two steps, we tested a system which...

journal_title：Anaesthesia

authors： Pattinson KT,Bowes M,Wise RG,Parkes MJ,Morrell MJ

更新日期：2005-05-01 00:00:00

abstract：:We report three deaths following percutaneous dilatational tracheostomy in a series of 1187 procedures undertaken in a single intensive care unit over a 13-year period. All deaths were due to severe haemorrhage. The first patient died during the procedure from uncontrollable haemorrhage from the innominate vein. Delay...

journal_title：Anaesthesia

authors： McCormick B,Manara AR

更新日期：2005-05-01 00:00:00

abstract：:A debate has emerged in recently published studies about the optimum cardiopulmonary bypass temperature for good neurological outcome - warm vs. cold, i.e. normothermic vs. hypothermic. Although many comparative studies have been performed, the results of these studies are inconclusive and are difficult to interpret. ...

journal_title：Anaesthesia

authors： Shaaban Ali M,Harmer M,Kirkham F

更新日期：2005-04-01 00:00:00

abstract：:The investigation of anaphylactic reactions in the peri-operative period is difficult. Elevation of serum tryptase levels is a good indicator of an anaphylactic event but the ability of subsequent investigations to identify the drug(s) responsible for the reaction is still potentially unreliable. The aim of this study...

journal_title：Anaesthesia

authors： Sudheer PS,Hall JE,Read GF,Rowbottom AW,Williams PE

更新日期：2005-03-01 00:00:00

abstract：:The purpose of this study was to examine the effect of low dose halothane on the acute ventilatory response to hypercapnia, and to assess whether arousal (due to audiovisual (AV) stimulation or pain) modulates the response to halothane. Single step increases in end-tidal Pco(2) using dynamic end-tidal forcing were per...

journal_title：Anaesthesia

authors： Pandit JJ,Moreau B

更新日期：2005-02-01 00:00:00